Nutritional factors and metabolic variables in relation to the risk of coronary heart disease: A case control study in Armenian adults

Moghadam, Ezatollah Fazeli and Tadevosyan, Artashes and Fallahi, Ebrahim and Goodarzi, Reza (2017) Nutritional factors and metabolic variables in relation to the risk of coronary heart disease: A case control study in Armenian adults. DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS, 11. pp. 7-11. ISSN 1871-4021

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Abstract

Abstract Introduction: Dietary factors can affect the coronary heart disease (CHD). Results of previous studies on the association between the diet and CHD are not consistent in different countries. There were no data on this association in Armenia. Objective: Aims of this case-control study were to evaluate the association between nutritional factors and CHD among Armenians in Yerevan. Methods: During 2010 and 2011, we randomly selected 320 CHD patients with a diagnosis of CHD less than 6 months and 320 subjects without CHD (>= 30 years old) from the hospitals and polyclinics in Yerevan. Dietary intakes with 135 food items over the previous 12 months were evaluated using a semi-quantitative food frequency questionnaire. Results: After adjusting for some CHD risk factors higher intakes of polyunsaturated fatty acids (PUFA) and monounsaturated fatty acids (MUFA) were associated with a reduced risk of CHD, while this association was not witnessed for saturated fatty acids (SFA). In addition, findings indicated an inverse relation between vitamins (E, B6 and B12, folic acid) and fiber with CHD. In this population, smoking, hypertension, and metabolic syndrome (MetS) were significantly more common among patients with CHD. Conclusion: The intake of vitamins E, B6 and B12, folic acid, PUFA, MUFA and fiber appeared to be predictors of CHD, independently of other risk factors. (C) 2016 Diabetes India. Published by Elsevier Ltd. All rights reserved. Keywords Author Keywords:Dietary factors; Coronary heart disease; Metabolic syndrome; Vitamins; Armenia

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