Variable number of tandem repeats profiles and antimicrobial resistance patterns of Staphylococcus haemolyticus strains isolated from blood cultures in children

Hosseinkhani, Faride and Jabalameli, Fereshteh and Nodeh Farahani, Narges and Taherikalani, Morovat and van Leeuwen, Willem B. and Emaneini, Mohammad (2015) Variable number of tandem repeats profiles and antimicrobial resistance patterns of Staphylococcus haemolyticus strains isolated from blood cultures in children. Journal of Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases.

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Abstract

Staphylococcus haemolyticus is a healthcare-associated pathogen and can cause a variety of lifethreatening infections. Additionally, multi-drug resistance (MDR), in particular methicillin-resistant S. haemolyticus (MRSH) isolates, have emerged. Dissemination of such strains can be of great concern in the hospital environment. A total number of 20 S. haemolyticus isolates from blood cultures obtained from children were included in this study. A high prevalence of MDR-MRSH isolates with high MIC values to vancomycin was found and 35% of the isolates were intermediate resistant to vancomycin. Multilocus variable number of tandem repeats analysis (MLVF) revealed 5 MLVF types among 20 isolates of S. haemolyticus. Twelve isolates shared the same MLVF type and were isolated from different wards in a pediatric hospital in Iran. This is a serious alarm for infection control; i.e. in the absence of adequate infection diagnostics and infection control guidelines, these resistant strains can spread to other sectors of a hospital and possibly among the community

Item Type: Article
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samira sepahvandy
Date Deposited: 23 Oct 2017 12:00
Last Modified: 23 Oct 2017 12:00
URI: http://eprints.lums.ac.ir/id/eprint/626

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