Dialysis adequacy in chronic hemodialysis patients in Shohada Ashayer Hospital, Khorramabad, Lorestan, Iran

Azita, Zafar Mohtashami and Babak, Hadian and GHolam Reza, Lashkarara* and Fatemeh, Mahdipanah (2016) Dialysis adequacy in chronic hemodialysis patients in Shohada Ashayer Hospital, Khorramabad, Lorestan, Iran. Yafte, 18 (4).

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Abstract

Background : Chronic kidney disease is an important health issue that its prevalence is increasing both in the worldwide and in our country. In the end stage renal disease (ESRD), lifelong renal replacement therapy with hemodialysis (the most frequent), peritoneal hemodialysis or kidney transplantation is required. Hemodialysis is the most frequent. Hemodialysis adequacy and nutritional status are associated with mortality rates of these patients. Materials and Methods: A descriptive epidemiologic study in which chronic renal failure patients with at least three months of hemodialysis history at Shohada hospital were recorded. Blood and urine samples were drawn and delivered to the specified laboratory and examined by the same person. Hemodialysis adequacy and protein catabolism rate were calculated. Data were analyzed with a significant level of 0.05 by SPSS version 16 statistical software. Results: Fifty-two patients (65.8 percent) out of 79 patients were male and 27(34.2%) were female. The mean age of patients was nearly 62 years. Further, the mean of hemodialysis adequacy and protein catabolism of patients were 1.2 and 1.83, respectively. Hemodialysis adequacy was associated with sex, age, BMI, and diabetes. Hemodialysis adequacy in non-diabetics was better (higher) than diabetics. Seventy patients (88.6 percent) had protein catabolism rate of 1.2 or more. Conclusion: Hemodialysis adequacy in women is better than in men, possibly related to their body size. Hemodialysis adequacy of older or fat patients was less than younger or low-weight ones, s probably because of declining muscle mass and a resultant decrease in creatinine. Protein catabolism rate was at an acceptable range in most patients. It is recommended to extend the duration of each session of hemodialysis, hemodialysis days at week, and the prevention and elimination of re-circulation in order to increase hemodialysis adequacy Keywords: Hemodialysis adequacy, Protein catabolism rate, Chronic kidney disease, Hemodialysis

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