Study of prevalence of human cytomegalovirus (HCMV) antibodies among patients HIV/AIDS in Kurdistan province, 2015

Omati, Arezoo and Bidarpour, Farzam and Rahmani*, KHaled and Karimi, Mohamad (2016) Study of prevalence of human cytomegalovirus (HCMV) antibodies among patients HIV/AIDS in Kurdistan province, 2015. Yafte, 18 (3).

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Abstract

Background : Cytomegalovirus (CMV) infection is one of the most common causes of death in people with immune deficiency diseases such as: organ or tissue recipients, patients with HIV/AIDS and newborn infants. The aim of this study was to determine the prevalence of anti-CMV antibodies in patients with HIV/AIDS in the Kurdistan province. Materials and Methods: This cross-sectional study carried out on 151 patients with HIV/AIDS covered by behavioral health counseling centers in Kurdistan province, 2015. For all patients the values of CMV antibodies, include IgG and IgM, were determined by ELISA technique and Diagnostic Kits (EIA WELL, Rome, Italy). Data analyses were done by use of t-test and multiple linear regression tests in stata software, version 13. Results: 116 (76.8%) and 35 (23.2%) of the patients were male and female, respectively. Mean (SD) age of the patients were 39.3 (9.1) years. All studied patients were found positive for CMV-IgG (prevalence=100%), whereas only one case (0.7%) was found positive for CMV-IgM. The relationship between age and CMV-IgG levels was statistically significant. Conclusion: The results showed that high prevalence of CMV in patients with HIV/AIDS, so in addition to paying more attention to the issue of HIV and CMV co-infection, about value of early antiretroviral treatment conducting further studies seems necessary. Keywords: Cytomegalovirus, HIV/AIDS, Prevalence.

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