Maleki-Sadeghi, Nazanin and Rahmani, Parisa and Aghsaeifard, Ziba and Heidari, Ghobad (2020) Effects of aminophylline on the levels of neutrophil gelatinase-associated lipocalin (NGAL) in asphyxiated term neonates. The Journal of Metabolic Diseases.
Full text not available from this repository.Abstract
Objective: Our study evaluates the effects of aminophylline in the reduction of NGAL levels in perinatal asphyxia. Methods: Term neonates with hypoxic ischaemic encephalopathy who were divided into two groups, the treatment and placebo. Urine NGAL levels were measured on day one and four of the treatment using BIOPORTO kits in both the groups. Results: Day 1 NGAL levels were not statistically different in either group irrespective of the age, gender and the mode of delivery. on 4th day, NGAL in treatment group significantly decreased as compared to day 1 levels and placebo day-4 levels. significant differences were seen between first and fourth day NGAL levels among children with normal and caesarean birth and among female and male neonates. Conclusions: Following the treatment with aminophylline, NGAL levels in asphyxiated neonates are likely to reduce. Further studies based on other kidney dysfunction parameters can lead to the better and accurate conclusions. Keywords: NGAL, aminophylline, renal failure, asphyxiated neonates
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Faculty of Medicine, Health and Life Sciences > School of Medicine |
| Depositing User: | samira sepahvandy |
| Date Deposited: | 12 May 2020 07:45 |
| Last Modified: | 12 May 2020 07:45 |
| URI: | http://eprints.lums.ac.ir/id/eprint/2071 |
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