Latent Class Analysis of DSM-5 Criteria for Opioid Use Disorders: Results from the Iranian National Survey on Mental Health

Tarrahi, Mohammad Javad and Rahimi-Movaghar, Afarin and Zeraati, Hojjat and Motevalian, Seyed Abbas and Esmaeili, Masoumeh Amin and Hajebi, Ahmad and Sharifi, Vandad and Radgoodarzi, Reza and Hefazi, Mitra and Fotouhi, Akbar (2015) Latent Class Analysis of DSM-5 Criteria for Opioid Use Disorders: Results from the Iranian National Survey on Mental Health. Eur Addict Res, 21. pp. 144-152.

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Abstract

Background: Assessments of DSM-IV and DSM-5 criteriawith sample populations of opioid users are limited. Thisstudy aimed to determine the number of latent classes inopioid users and assessment of the proposed revisions to theDSM-5 opioid use disorder (OUD) criteria. Methods: Datacame from the 2011 Iranian National Mental Health Survey(IranMHS) on 7,886 participants aged 15–64 years living inIran. We used the Composite International Diagnostic Interview(CIDI) version 2.1 in all respondents who indicated usingopioids at least 5 times in the previous 12 months (n =236). Results: A three-class model provided the best fit of allthe models tested. Classes showed a spectrum of severity that was compatible with the DSM-5 classification. ‘Legalproblems’ and ‘desire to cut down’ showed poor discriminationbetween classes. The weighted prevalence of OUD usingDSM-5 was 20.7% higher than with DSM-IV. Conclusions:Results support the grouping based on severity of symptoms,combining abuse and dependence into a single diagnosis,omitting legal problems, and addition of craving as anew criterion.Key WordsDSM-5 · DSM-IV · ICD-10 · Diagnosis · Opiate dependence ·Opioid-related disorders · Iran

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