The Role of Iranian Medicinal Plants of the Asteraceae Family in Pain Therapy: A Systematic Review

Nadri, Sedigheh and Mahmoudvand, Hormoz (2021) The Role of Iranian Medicinal Plants of the Asteraceae Family in Pain Therapy: A Systematic Review. Herbal Medicines Journal, 6 (1).


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Asteraceae or Compositae is considered as one of the main flowering plants around the world which presently have more than 23,600 accepted species from 1,620 genera and 13 subfamilies. The present study aims to systematically review the role of Iranian medicinal plants of the family Asteraceae in pain therapy. We searched several databases, including Scopus, PubMed, Web of Science, EMBASE, Google Scholar, MagIran, and SID without time limitation for publications related to antinociceptive effects of Iranian medicinal herbs of the Ateraceae family. Studies in any language were entered in the search phase if they had an English abstract. Of the 1080 papers obtained from all of the databases up to 2020, 20 articles were reliable and were scrutinized. The most abundant parts of these plants are aerial parts (17 papers, 85%). Based on the obtained results, the most abundant products were hydroalcohol extract (10 papers, 45.5%) and essential oils (8 papers, 40%) of the medicinal herbs of the Asteraceae family. The most frequently tests used were formalin test (77.3%), followed by writhing test (54.5%) and tail-flick test (36.4%). The findings of the present review demonstrated that the Iranian medicinal herbs of the Asteraceae family are generally used to treat and reduce pain. Although herbs in this family may be considered as alternative agents for pain treatment, further studies are required to clear the accurate anti-nociceptive mechanisms as well as toxicity of these plants in human subjects

Item Type: Article
Subjects: R Medicine > RM Therapeutics. Pharmacology
R Medicine > RS Pharmacy and materia medica
R Medicine > RV Botanic, Thomsonian, and eclectic medicine
R Medicine > RZ Other systems of medicine
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samira sepahvandy
Date Deposited: 15 Jun 2022 04:38
Last Modified: 15 Jun 2022 04:38

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