The effect of eight weeks of combined training (resistance-aerobic) on serum immunoglobulin G concentration and liver injury indices in elderly men

Delshad*, amir and Dashti, maryam sadat and Astarabadi, akram (2021) The effect of eight weeks of combined training (resistance-aerobic) on serum immunoglobulin G concentration and liver injury indices in elderly men. Yafteh, 22 (4).

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Abstract

Background: Today, participation in regular sports programs is an undeniable need for prevention of diseases and improving the quality of life of the elderly. Therefore, the aim of this study was to investigate the effect of a selected combined training course on immunoglobulin G concentration and liver injury index in elderly men. Materials and Methods: In this quasi-experimental study, 20 elderly men in the age group of 65-55 years were randomly divided into two groups of combined exercise and control. Combined exercises, including aerobic activity with an intensity of 60 to 74% of the stored heart rate and strength exercises with 50 to 75% of 1RM were performed during 8 weeks and three sessions per week. Blood samples were collected 24 hours before and 48 hours after the last training session to measure serum AST, ALT and IgG levels. To analyze the data from ANKOVA test and to compare intra-group differences, paired t-test was performed at a significant level of P <0.05. Results: The results showed that there was a significant difference between the combination and control groups in serum concentrations of AST (P =0.003), ALT (P=0.004) and IgG (P=0.041). Paired t-test results showed a significant decrease in post-test compared to pre-test ALT (P=0.048), AST (P=0.007) and IgG (P=0.02). Conclusion: The results of the present study showed that combined activities are an effective factor in preventing liver damage and strengthening the immune system of the elderly. Combined training can be a good exercise protocol to maintain health in these people. Keywords: Alanine transferase, Aspartate aminotransferase, Immunoglobulin G, Elderly.

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