Cheraghipour, Kourosh and Beiranvand, Marjan and Zivdari, Masoomeh and Amiri, Sana and Masoori , Leila and Abbaszadeh, Saber and Moradpour, Kobra and Marzban, Abdolrazagh (2020) In vitro potential effect of Pipper longum methanolic extract against protoscolices of hydatid cysts. Experimental Parasitology.
Full text not available from this repository.Abstract
This study aimed to evaluate the efficacy of methanolic extract of P. longum (PLM) against protoscolices of hydatid cyst in vitro. Four different concentrations of PLM extract (25, 50, 100 and 150 mg/ml) were used for the experiments. The metabolites in the PLM extract were characterized by Gas chromatography-mass spectrometry (GC-MS). The results showed the highest lethality of PLM extract in 50 mg/ml for 60 min exposure. The IC50 value obtained about 20 mg/ml for 60 min of PLM extract exposure. In this study, valuable findings were obtained for the first time about the scolicidal activity of P. longum, which is expected to conduct further studies in this field in the future.
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > RM Therapeutics. Pharmacology |
| Divisions: | Faculty of Medicine, Health and Life Sciences > School of Medicine |
| Depositing User: | lorestan university |
| Date Deposited: | 16 Dec 2020 07:47 |
| Last Modified: | 16 Dec 2020 07:47 |
| URI: | http://eprints.lums.ac.ir/id/eprint/2480 |
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