Seroprevalence and risk factors of Toxoplasma gondii infection among healthy blood donors in south-east of Iran

Mahmoudvand, h and Saedi Dezaki, Ebrahim and Soleimani, s and Baneshi,, v R. and Kheirandish, f and vEzatpour,, b and Zia-ali, n and UNSPECIFIED (2015) Seroprevalence and risk factors of Toxoplasma gondii infection among healthy blood donors in south-east of Iran. PARASITE IMMUNOLOGY, 37 (7). pp. 362-367. ISSN 0141-9838

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Abstract

This prospectivecross-sectional study was aimed to evaluate the prevalence of IgM and IgG anti-T. gondii antibodies and the associated risk factors among healthy blood donors in Kerman province, south-eastern Iran. Structured questionnaires (before the donors gave blood) were used to obtain information on risk factors for infection. Totally, 500 serum samples from healthy blood donors of Kerman Blood Transfusion Organization (KBTO) at Kerman, Iran, were screened for IgG and IgM anti-T.gondii antibodies by enzyme-linked immunosorbent assay (ELISA) and Roche Elecsys Toxo IgM assay. Real-time PCR was used to detect DNA of T.gondii in the IgM-positive samples. Seroprevalence of IgG and IgM anti-T.gondii antibodies was 288% and 32%, respectively. In the multiple logistic regression, it could be observed that living in rural regions, having B blood type, being in contact with cats, consuming raw vegetables and raw milk/egg and doing agricultural activities were independent risk factors for Toxoplasma seropositivity. T.gondii DNA was also found in one (90%) of IgM-positive samples. In this study, it was found that T.gondii infection was present among healthy blood donors in south-east of Iran. Therefore, it is suggested to design screening programmes for preventing transfusion-transmitted toxoplasmosis.

Item Type: Article
Subjects: G Geography. Anthropology. Recreation > GC Oceanography
Depositing User: sobhan rezaiian
Date Deposited: 23 Oct 2017 12:05
Last Modified: 23 Oct 2017 12:05
URI: http://eprints.lums.ac.ir/id/eprint/706

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