RISK FACTORS OF CHILDREN'S ASTHMA (6-12 YEARS OLD) IN KHORRAMABAD, IRAN: A CASE CONTROL STUDY

Amiri, Ali and Ghaderi, Nishteman and Obeidavi, Zia and Khorramabadi, Saber and Torkashvand, Javad and Sheikhi, Elham and Beiranvand, Behrouz (2016) RISK FACTORS OF CHILDREN'S ASTHMA (6-12 YEARS OLD) IN KHORRAMABAD, IRAN: A CASE CONTROL STUDY. The IIOAB Journal – Institute of Integrative Omics and Applied Biotechnology Journal, 7 (8). pp. 1-5.

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Abstract

The aim of this study is to investigate the risk factors involved in the morbidity of asthma in Khorramabad city and its suburban areas. In the present case-control research, all the patients who had referred to the Shahid Rahimi Hospital and a pulmonary disease sub-specialist’s office in Khorramabad in 2015 and had been diagnosed with asthma by a pulmonary disease sub-specialist and based on the criteria of Global Initiative for Asthma (GINA) were enrolled in the study. The census taking sampling method was used and all patients with immunodeficiency, congenital diseases, chronic allergic pulmonary diseases or sinusitis were excluded. The control group that matched the experimental group in terms of age, sex and the place of residence were selected from among those referring to the ophthalmological and dermatological clinics of the Shahid Rahimi Hospital. The data collection instrument used in this study was a questionnaire that included items related to the demographic information of the patients, and also questions regarding the patient’s economic and social situation as well as the patient's clinical symptoms from birth until the present. All parents of the selected children signed written consents regarding their participation in the study. The data were analyzed using SPSS software. The mean age of the patients was 8.5±2.1 and 60.3 percent of the patients were male. The average age of the mothers of asthmatic children was higher than the mothers of healthy children and this difference was statistically significant (P-value= 0.009). The mean duration of breastfeeding in healthy children was higher than the asthmatic children and this difference was Statistically significant (P-value= 0.001). There was observed a statistically significant relationship between a background of asthma or allergy among first-degree relatives and the development of asthma in the patients themselves (P-value < 0.05). The children of highly educated parents were less likely to develop allergic diseases and asthma, which could be attributed to the knowledge of the parents about various diseases. Given the risk factors, it can be concluded that acquired factors can play an important role in the occurrence of this disease in children.

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