Photodynamic therapy effect on cell growth inhibition induced byRadachlorin and toluidine blue O on Staphylococcus aureus andEscherichia coli: An in vitro study

Fekrazad, Reza and Zare, Hadi and Mohammadi Sepah Vand, Sara Photodynamic therapy effect on cell growth inhibition induced byRadachlorin and toluidine blue O on Staphylococcus aureus andEscherichia coli: An in vitro study. Photodiagnosis and Photodynamic Therapy.

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Abstract

tumordetection and for the treatment of cancer as well as nontumoral diseases, such as psoriasis (2), bacterialand viral eradication.Material and method: Effect of two photosensitizer (toluidine blue O (TBO) and Radachlorin was investi-gated on Staphylococcus Aureus ATCC 25923 (American Type Culture Collection) and Escherichia coli (ATCC25922).Results: PDI by TBO caused S. aureus 5.83 log10 killing (P.Value < 0.0001) and reduce 0.08 log 10 in E. coli(P.Value = 0.321). PDI by Radachlorin®reduce 0.17 log 10 in E. coli (P.Value < 0.0001) and S. aureus showed6.1 log 10 colony count reduction.Conclusion: Within the limitation of this in vitro study, we can conclude that both PS have the same effecton S. aureus and E. coli with good inhibition effect on S. aureus and partial inhibition effect E. coli

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Depositing User: sobhan rezaiian
Date Deposited: 07 May 2017 05:30
Last Modified: 07 May 2017 05:30
URI: http://eprints.lums.ac.ir/id/eprint/552

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