Fekrazad, Reza and Zare, Hadi and Mohammadi Sepah Vand, Sara (2017) Photodynamic therapy effect on cell growth inhibition induced byRadachlorin and toluidine blue O on Staphylococcus aureus andEscherichia coli: An in vitro study. Photodiagnosis and Photodynamic Therapy.
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Abstract
tumordetection and for the treatment of cancer as well as nontumoral diseases, such as psoriasis (2), bacterialand viral eradication.Material and method: Effect of two photosensitizer (toluidine blue O (TBO) and Radachlorin was investi-gated on Staphylococcus Aureus ATCC 25923 (American Type Culture Collection) and Escherichia coli (ATCC25922).Results: PDI by TBO caused S. aureus 5.83 log10 killing (P.Value < 0.0001) and reduce 0.08 log 10 in E. coli(P.Value = 0.321). PDI by Radachlorin®reduce 0.17 log 10 in E. coli (P.Value < 0.0001) and S. aureus showed6.1 log 10 colony count reduction.Conclusion: Within the limitation of this in vitro study, we can conclude that both PS have the same effecton S. aureus and E. coli with good inhibition effect on S. aureus and partial inhibition effect E. coli
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > R Medicine (General) |
| Depositing User: | samira sepahvandy |
| Date Deposited: | 07 May 2017 05:30 |
| Last Modified: | 23 Oct 2017 16:29 |
| URI: | http://eprints.lums.ac.ir/id/eprint/552 |
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