Leveraging nationwide epidemiological big data for diabetes modeling and disease surveillance: an innovative approach for advancing public health policy in developing countries

Hayati, Hadi and Askari Zahabi, Razieh (2025) Leveraging nationwide epidemiological big data for diabetes modeling and disease surveillance: an innovative approach for advancing public health policy in developing countries. BMC Res Notes.

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Abstract

Objective: Diabetes is escalating into a global crisis, with low- and middle-income countries bearing the heaviest burden. Yet few nations openly harness nationwide health data to guide precise, evidence-based interventions. This study pioneers the large-scale integration of Iran's decade-long electronic prescription records with advanced modelling tools to illuminate national and regional dynamics in antidiabetic drug use. By fusing big data analytics with policy-driven insight, our aim was not only to expose inequities and inefficiencies but to create a transferable blueprint for equitable, guideline-aligned diabetes care worldwide. Results: Across 84 million prescriptions (2013-2023), metformin dominated treatment, but novel agents such as DPP-4 and SGLT2 inhibitors surged after 2017, reshaping the therapeutic landscape. Stark contrasts emerged: first-line metformin initiation ranged from 58.3% in underserved Sistan & Baluchestan to 91.7% in resource-advantaged Tehran; inappropriate early adoption of new agents and premature insulinisation persisted in several regions. These patterns mirror global fault lines-where innovation coexists with inequity-and underscore the urgency for adaptive, data-led policy. Our proposed multi-tier model-combining real-time digital surveillance, prescriber upskilling, and patient empowerment-offers a novel, globally relevant pathway for transforming big data into equitable, future-ready diabetes strategies in resource-limited health systems

Item Type: Article
Subjects: R Medicine > RZ Other systems of medicine
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: lorestan university
Date Deposited: 11 Oct 2025 04:31
Last Modified: 11 Oct 2025 04:31
URI: http://eprints.lums.ac.ir/id/eprint/5230

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