Jalali-Zefrei, Fatemeh and Mousavi, Seyed Mehdi and Delpasand, Kourosh and Shourmij, Mohammad and Farzipour, Soghra (2024) Role of Non-coding RNAs on the Radiotherapy Sensitivity and Resistance in Cancer Cells. Current gene therapy.
Full text not available from this repository.Abstract
Radiotherapy (RT) is an integral part of treatment management in cancer patients. However, one of the limitations of this treatment method is the resistance of cancer cells to radiotherapy. These restrictions necessitate the introduction of modalities for the radiosensitization of cancer cells. It has been shown that Noncoding RNAs (ncRNAs), along with modifiers, can act as radiosensitivity and radioresistant regulators in a variety of cancers by affecting double strand break (DSB), wnt signaling, glycolysis, irradiation induced apoptosis, ferroptosis and cell autophagy. This review will provide an overview of the latest research on the roles and regulatory mechanisms of ncRNA after RT in in vitro and preclinical research. Keywords: Non-coding RNA; cancer; longer ncRNA; miRNA.; radioresistance; radiosensivity; radiotherapy.
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > R Medicine (General) R Medicine > RC Internal medicine R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) R Medicine > RZ Other systems of medicine |
| Divisions: | Faculty of Medicine, Health and Life Sciences > School of Medicine |
| Depositing User: | samira sepahvandy |
| Date Deposited: | 12 May 2024 07:14 |
| Last Modified: | 12 May 2024 07:14 |
| URI: | http://eprints.lums.ac.ir/id/eprint/4767 |
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