Evaluating the effect of glycerol on increasing the safety and efficiency of hyperthermic laser lipolysis

Vahidian, Afsane and Momayezan Marnani, Parvaneh and Mehdizadeh, Alireza and Rezaeian, Abbas and Ostovari, Mohsen (2024) Evaluating the effect of glycerol on increasing the safety and efficiency of hyperthermic laser lipolysis. Lasers in medical science.

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Abstract

Abstract This study aimed to investigate the effect of glycerol as an Optical Clearing Agent on the temperature profile of the skin during HyperThermic Laser Lipolysis using computer simulation. In this study, a three-layer model of the skin was used to simulate HyperThermic Laser Lipolysis. The Monte Carlo MCML code was used to investigate the propagation of laser photons inside skin tissue. The energy absorbed from photons is used as a heat source to determine the increase in temperature and assess thermal damage in the layers of the skin. The finite element method in COMSOL software was used for calculation. The simulation of single-pulse radiation exposure with and without applying glycerol to the skin model was investigated to assess the impact of glycerol. Glycerol decreases the temperature and thermal damage to the epidermis layer while increasing the temperature of the fat layer. Moreover, the presence of glycerol increases the depth of fat cell destruction. Glycerol, as a supplement, significantly improves the efficacy of HyperThermic Laser Lipolysis. Keywords: Glycerol; Hyperthermic laser lipolysis; Monte-Carlo simulation; Non-invasive fat reduction; Numerical modeling; Optical clearing agent.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
R Medicine > RZ Other systems of medicine
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samira sepahvandy
Date Deposited: 15 Apr 2024 05:55
Last Modified: 15 Apr 2024 05:55
URI: http://eprints.lums.ac.ir/id/eprint/4719

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