Heart targeted nanoliposomal/nanoparticles drug delivery

Cheraghi, Mostafa and Negahdari, Babak and Daraee, Hadis and Eatemadi, Ali Heart targeted nanoliposomal/nanoparticles drug delivery. BIOMEDICINE & PHARMACOTHERAPY.

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Abstract

Nanoliposomes are type of nano-sized vesicles made of bi-layered phospholipid membranes with an aqueous interior. They have been demonstrated to deliver several materials like low molecular weight drugs, imaging agents, peptides, proteins, and nucleic acids. Nanoliposomes have been demonstrated to slowly release an encapsulated drug, thereby leading to sustained exposure to target region and improved efficacy. This ability of nano-liposomes can be harnessed to deliver therapeutic agents precisely to the infarcted heart. Accordingly, this article will review recent developments in the application of nano liposomes and nanoparticles as drug delivery systems to treat cardiovascular related disorders such as atherosclerosis, restenosis and myocardial infarction. (C) 2016 Elsevier Masson SAS. All rights reserved.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Depositing User: sobhan rezaiian
Date Deposited: 30 Apr 2017 05:34
Last Modified: 30 Apr 2017 05:34
URI: http://eprints.lums.ac.ir/id/eprint/470

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