Green synthesis of gold nanoparticles (AuNPs) using aqueous extract and essential oils from Satureja Khuzestanica Jamzad: evaluation of their antibacterial and antifungal activities

Rashidipour, Marzieh and sepahvand, Asghar and Soroush, Setareh and Ashrafi, Behnam (2023) Green synthesis of gold nanoparticles (AuNPs) using aqueous extract and essential oils from Satureja Khuzestanica Jamzad: evaluation of their antibacterial and antifungal activities. Biologia.

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Abstract

The biosynthesis of nanoparticles has drawn fervent interest because of its environmental friendliness and broad applications in biomedicine. In this study, gold nanoparticles (AuNPs) were synthesized employing Satureja Khuzistanica Jamzad (SKJ) extract (AuNPs-EX) and essential oils (AuNPs-EO). Accordingly, physicochemical characterization of the biosynthesized AuNPs was performed using conventional methods, including visual observation, UV–Vis spectrophotometry, particle size analysis, zeta potential, XRD, FTIR, and FESEM. The results showed the successful formation of AuNPs with cubic and spherical morpholo- gies and sizes of 244.96 and 252.83 nm for AuNPs-EX and AuNPs-EO, respectively. Additionally, AuNPs showed long-term stability, as reflected by their high negative surface charge. Also, the antibacterial and antifungal properties of AuNPs were demonstrated using a microbroth dilution assay against three G+ bacterial standard strains (Bacillus cereus, Staphylococcus aureus, and Staphylococcus saprophyticus), three G− bacterial standard strains (Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae), and three fungal standard strains (Candida albicans, Aspergillus flavus, and Aspergillus fumigatus). Our results indicated that AuNPs-EO exhibited higher antibacterial and antifungal properties than SKJ essential oils. Taken together, the biosynthesis of AuNPs using SKJ may provide an eco-friendly approach for preparing metal nanoparticles and is a promising candidate for controlling infectious diseases.

Item Type: Article
Subjects: R Medicine > RZ Other systems of medicine
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: lorestan university
Date Deposited: 11 Nov 2023 05:13
Last Modified: 11 Nov 2023 05:13
URI: http://eprints.lums.ac.ir/id/eprint/4512

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