Investigating the protective effect of the methanolic extract of Salvia multicaulis on renal ischemia-reperfusion injuries in rats

Mirzania, Foroogh and Salimikia, Iraj and Ghasemian-Yadegari, Javad and Aalaei, Javid and Ghobadi, Mohammad Amin and Taheri Demneh, Majid and Nazarzadeh, Alireza (2023) Investigating the protective effect of the methanolic extract of Salvia multicaulis on renal ischemia-reperfusion injuries in rats. Health Biotechnology and Biopharma.

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Abstract

In this research the protective effects of the methanolic extract of S. multicaulis was evaluated in renal ischaemia-reperfusion injuries in rats. 42 male rats were divided into 6 groups. In the treatment groups 1-3, before causing ischemia in the kidneys, rats received 50, 100, and 150 mg/kg/day doses of the extract orally for 20 days, then ischaemia was created. In the evaluation of urea and creatinine factor, rosmarinic acid and extract dose of 150 mg/kg/day had a significant effect in reducing these two factors.

Item Type: Article
Subjects: R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samira sepahvandy
Date Deposited: 14 Aug 2023 09:02
Last Modified: 14 Aug 2023 09:02
URI: http://eprints.lums.ac.ir/id/eprint/4375

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