Colon cancer targeting using conjugates biomaterial 5-flurouracil

Soleiman Jaferian, Lorestan University of Medical Sciences and Ali Eatemadi, Lorestan University of Medical Sciences and Babak Negahdari, Tehran University of Medical Sciences (2016) Colon cancer targeting using conjugates biomaterial 5-flurouracil. Biomedicine & Pharmacotherapy. ISSN 0753-3322

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Abstract

There has been several research works on the development of an oral delivery system to deliver cytotoxic and chemo preventive agents directly at the targeted site of action with reduced unwanted side effects. The efficacy of the site-specific delivery system of a drug to colon has been proven to increase the drugs concentration at the target site, and thus requires a reduced dose of the drug with minimized side effects. This review includes discussion of the delivery systems of 5-FU using biodegradable materials and some significant outcomes in the pre-clinical development of 5-fluorouracil carriers for the colon cancer

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Depositing User: sobhan rezaiian
Date Deposited: 12 Mar 2017 06:05
Last Modified: 12 Mar 2017 06:05
URI: http://eprints.lums.ac.ir/id/eprint/436

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