Mashhadiabbas, Fatemeh and GholamiToghchi, Sanaz and Safarpour, Roohollah (2023) Central Granular Cell Odontogenic Tumor: Review of Cases Reported in the Last 71 years and Report of a Case. Chin Med Sci J.
Full text not available from this repository.Abstract
Central granular cell odontogenic tumors (CGCOTs) are rare, benign, slowly growing odontogenic neoplasms. Due to their uncertain histogenesis, CGCOTs are still not included as a distinct entity in the WHO classification (2017) of odontogenic tumors. We report a case of CGCOT involving the right side of maxillary anterior region of a 39-year-old white female. Immunohistochemical staining showed granular cells positively expressed CD68 and vimentin, and negatively expressed S-100 protein. Meanwhile, we searched PubMed, Google Scholar, and Scopus databases to summary the clinico-pathological features of 51 published cases of CGCOT. The results showed the granular cells of 28.6% cases were immunopositive for vimentin and CD68, and odontogenic epithelial cells positive immunoreactivity for cytokeratin. These findings reinforced the mesenchymal origin of granular cells and the odontogenic nature of epithelium islands.
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > RZ Other systems of medicine |
| Divisions: | Faculty of Medicine, Health and Life Sciences > School of Medicine |
| Depositing User: | samira sepahvandy |
| Date Deposited: | 26 Apr 2023 06:38 |
| Last Modified: | 26 Apr 2023 06:38 |
| URI: | http://eprints.lums.ac.ir/id/eprint/4193 |
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