Rezaeinasab, Rezvan and Jafari, Elham and Khodarahmi, Ghadamali (2022) Quinazolinone-based hybrids with diverse biological activities: A mini-review. Journal of Research in Medical Sciences.
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Abstract
Quinazolinone and quinazoline have been shown different pharmacological activities, namely anticancer, anti-inflammatory, anti-hyperlipidemia, analgesic, antihypertensive, and antibacterial. On the other hand, molecular hybridization is a structural modification technique in the design of new ligands which consist of two or more pharmacologically active molecules in one structure. Therefore, due to the importance of the biological activities of quinazolinones for the development of new therapeutic agents, this review emphasizes current findings on various quinazolinone-based hybrids in medicinal chemistry. Moreover, it highlights the biological activities and structure-activity relationship of these hybrids.
| Item Type: | Article |
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| Subjects: | R Medicine > RZ Other systems of medicine |
| Divisions: | Faculty of Medicine, Health and Life Sciences > School of Medicine |
| Depositing User: | samira sepahvandy |
| Date Deposited: | 14 Nov 2022 10:01 |
| Last Modified: | 14 Nov 2022 10:01 |
| URI: | http://eprints.lums.ac.ir/id/eprint/3982 |
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