In-vivo and in vitro assessments of the radioprotective potential natural and chemical compounds: A review

Javadi, Anis and Nikhbakht, Mohammad Reza and Ghasemian Yadegari, Javad and Rustamzadeh, Auob and Mohammadi, Mohsen and Shirazinejad, Alireza and Azadbakht, Saleh and Abdi, Zahra (2022) In-vivo and in vitro assessments of the radioprotective potential natural and chemical compounds: A review. Int J Radiat Biol.

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Abstract

Methods: The authors search for keywords including In vitro, In vivo, Radioprotective, Ionizing radiation, and Vitamin in ScienceDirect, Scopus, Pubmed, and Google Scholar databases to access previously published articles and search for more reference articles on the role of radioprotective materials from natural and chemical compounds. Results: Radiation exposure can produce reactive oxygen species (ROS) in the body, however most of which are eliminated by the body's natural mechanisms, but when the body's antioxidant systems do not have enough ability to neutralize free radicals, oxidative stress occurs, which causes damage to DNA and body tissues. Therefore, it is necessary use of alternative substances that reduce and inhibit free radicals. Conclusion: In general, recommended that antioxidant component(s) can be protect tissue damages in humans or animals, due to the their ability to scavenge free radicals generated by ionizing radiation.

Item Type: Article
Subjects: R Medicine > RZ Other systems of medicine
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: lorestan university
Date Deposited: 15 May 2022 04:00
Last Modified: 15 May 2022 04:00
URI: http://eprints.lums.ac.ir/id/eprint/3768

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