Heart targeted nanoliposomal/nanoparticles drug delivery: An updated review

Mostafa Cheraghia, Lorestan University of Medical Sciences and Babak Negahdarib, Tehran University of Medical Sciences and Hadis Daraeeb, Lorestan University of Medical sciences and Ali Eatemadib, Lorestan University of Medical sciences (2016) Heart targeted nanoliposomal/nanoparticles drug delivery: An updated review. Biomedicine & Pharmacotherapy, 86 (2017). pp. 316-323. ISSN 0753-3322

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Abstract

Nanoliposomes are type of nano-sized vesicles made of bi-layered phospholipid membranes with an aqueous interior. They have been demonstrated to deliver several materials like low molecular weight drugs, imaging agents, peptides, proteins, and nucleic acids. Nanoliposomes have been demonstrated to slowly release an encapsulated drug, thereby leading to sustained exposure to target region and improved efficacy. This ability of nano-liposomes can be harnessed to deliver therapeutic agents precisely to the infarcted heart. Accordingly, this article will review recent developments in the application of nano liposomes and nanoparticles as drug delivery systems to treat cardiovascular related disorders such as atherosclerosis, restenosis and myocardial infarction. Keywords: Nano-liposomes Myocardial infarction Nanoparticles Atherosclerosis

Item Type: Article
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Depositing User: sobhan rezaiian
Date Deposited: 01 Mar 2017 05:40
Last Modified: 01 Mar 2017 05:40
URI: http://eprints.lums.ac.ir/id/eprint/371

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