Radiofrequency ablation of parathyroid adenomas causing primary hyperparathyroidism: A report of 27 patients

Ebrahiminik, Hojat and Chegeni, Hossein and Mosadegh Khah, Ali and Salouti, Rambod and Beiranvand, Behrouz (2022) Radiofrequency ablation of parathyroid adenomas causing primary hyperparathyroidism: A report of 27 patients. J Clin Ultrasound ..

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Abstract

Purpose: To study treatment outcome of parathyroid adenomas using ultrasound-guided radiofrequency ablation. Methods: Twenty-seven patients with a single adenoma of the parathyroid gland were included in the study. Using color Doppler ultrasonography, the lesion and its characteristics were determined, and dextrose was injected to dissect the gland from the surrounding structures. The ablation process was done with 6-12 watts of power. Results: No complications were seen in any of the subjects. A significant reduction was seen in serum parathyroid hormone (PTH) and calcium levels after treatment. PTH levels showed a median decrease of 13.8%, and a median decrease of 8.2% was seen in serum calcium levels (p < 0.001). Phosphorus levels did not change significantly after treatment. In 1-month follow-up of patients, the lesion size had decreased considerably. In long-term follow-up, 11 of 20 patients having subsequent imaging had indistinguishable lesions. Conclusion: Our results showed that RFA of parathyroid adenomas caused a significant reduction in biomedical indicators of disease and resulted in a significant reduction or disappearance of the lesion in the majority of the patients while having no considerable complications.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Depositing User: samira sepahvandy
Date Deposited: 04 Apr 2022 03:45
Last Modified: 04 Apr 2022 03:45
URI: http://eprints.lums.ac.ir/id/eprint/3709

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