Pulmonary vaccine delivery: An emerging strategy for vaccination and immunotherapy

Masjedi, Moein and Montahaei, Talieh and Sharafi, Zeinab and Jalali, Atefeh (2022) Pulmonary vaccine delivery: An emerging strategy for vaccination and immunotherapy. Journal of Drug Delivery Science and Technology.


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Vaccination has been known as the most successful health strategy for the prevention of infectious diseases, and their subsequent disability conditions. Conventional vaccination is based on parenteral administration and therefore requires needles, cold-chain storage and distribution. To meet these drawbacks, new strategies such as pulmonary vaccination have brought new insights into immunotherapy and vaccination. Among novel strategies, nanoparticulate vaccine delivery systems play an undeniable role in targeting and depositing of antigenic (nano-)microparticles in particular regions of the respiratory tract, engineering the inhalable powders, altering the release profile and pharmacokinetic features of vaccines. This study aims to review pulmonary immune system, pulmonary vaccine delivery, micro and nanocarriers for pulmonary vaccine delivery, and nanotechnology-based pulmonary vaccines. Graphical

Item Type: Article
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samira sepahvandy
Date Deposited: 02 Mar 2022 05:37
Last Modified: 02 Mar 2022 05:37
URI: http://eprints.lums.ac.ir/id/eprint/3685

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