Fungal infection in cystic fibrosis

Sarvestani, Amirmehdi and Almasian, Mohammad and Nafari, Amirhossein (2021) Fungal infection in cystic fibrosis. Current Respiratory Medicine Reviews.

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Background: The prevalence of fungal infections has been increasing in recent years. Cystic fibrosis (CF) is a genetic disorder that affects organs such as the intestines, liver, pancreas, and especially the lungs. Introduction: Fungal pathogens are becoming a challenge in CF. Advanced medical science is associated with longer life expectancy in some patient groups. Method: A review was conducted on studies found on online databases, including Google Scholar, PubMed, and Scopus. Internet-based searches were performed on these databases for cystic fibro-sis, respiratory infections, and fungal infection profiling to identify all relevant studies published between 2010 and 2020. Result: Fungal pathogens most frequently isolated from the respiratory tract include the Aspergil-lus genus, the Candida genus, Scedosporium apiospermum, and the Rasamsonia genus. In cystic fi-brosis, these organisms usually colonize the respiratory and intestinal tracts and cause hypersensi-tivity responses and invasive diseases. Conclusion: Fungus-patient interactions are complicated and depend on various factors. Moreover, the emergence of drug-resistant species is a serious health issue, and the development of new treat-ments is crucial. © 2021 Bentham Science Publishers.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samira sepahvandy
Date Deposited: 01 Dec 2021 08:27
Last Modified: 01 Dec 2021 08:27

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