Variable number of tandem repeats profiles and antimicrobial resistance patterns of Staphylococcus haemolyticus strains isolated from blood cultures in children

Hosseinkhani, Faride and Jabalameli, Fereshteh and Nodeh Farahani, Narges and Taherikalani, Morovat and van Leeuwen, Willem B and Emaneini, Mohammad (2016) Variable number of tandem repeats profiles and antimicrobial resistance patterns of Staphylococcus haemolyticus strains isolated from blood cultures in children. journal pertain, 38.

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Abstract

ABSTRACT Staphylococcus haemolyticus is a healthcare-associated pathogen and can cause a variety of lifethreatening infections. Additionally, multi-drug resistance (MDR), in particular methicillin-resistant S. haemolyticus (MRSH) isolates, have emerged. Dissemination of such strains can be of great concern in the hospital environment. A total number of 20 S. haemolyticus isolates from blood cultures obtained from children were included in this study. A high prevalence of MDR-MRSH isolates with high MIC values to vancomycin was found and 35% of the isolates were intermediate resistant to vancomycin. Multilocus variable number of tandem repeats analysis (MLVF) revealed 5 MLVF types among 20 isolates of S. haemolyticus. Twelve isolates shared the same MLVF type and were isolated from different wards in a pediatric hospital in Iran. This is a serious alarm for infection control; i.e. in the absence of adequate infection diagnostics and infection control guidelines, these resistant strains can spread to other sectors of a hospital and possibly among the community. Keywords: S. haemolyticus, MLVF typing, multidrug resistance, blood culture, pediatric patients.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Depositing User: sobhan rezaiian
Date Deposited: 03 Oct 2016 07:01
Last Modified: 08 Nov 2017 20:13
URI: http://eprints.lums.ac.ir/id/eprint/319

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