Shakib, Pegah and Barati, Mahmood and Gholipourmalekabadi, Mazaher (2021) Antibiotic resistance pattern and molecular typing by pcr-rapd analysis in clinical isolates of pseudomonas aeruginosa from motahari hospital, tehran, iran. Journal of Kerman University of Medical Sciences.
Full text not available from this repository.Abstract
Background: Pseudomonas aeruginosa infection is one of the major challenges in burn patients. This organism is resistant to a wide range of antibiotics. The aim of this study was to investigate the antibiotic susceptibility and genetic relatedness in Pseudomonas aeruginosa isolated from patients admitted to Motahari Burn Center, Tehran, Iran. Methods: This study was conducted on 186 burn patients with Pseudomonas aeruginosa colonization following admission in Motahari Burn Center during one year. Antibiotic resistance test was performed by disc diffusion method and genetic relatedness was evaluated by PCR-RAPD analysis. Results: The highest and lowest percentage of resistance was observed against ceftizoxime and ciprofloxacin. The genotyping study by RAPD PCR technique revealed 57 different genotypes, among which RAPD 5, RAPD 8, and RAPD 9 were the most prevalent patterns and produced by 14%, 9%, and 7% of the isolates, respectively. Conclusion: In total, no association was found between RAPD genotypes and antibiotic resistance patterns, and death rate. © 2021, Kerman University of Medical Sciences. All rights reserved
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > RM Therapeutics. Pharmacology |
| Divisions: | Faculty of Medicine, Health and Life Sciences > School of Medicine |
| Depositing User: | lorestan university |
| Date Deposited: | 15 Sep 2021 05:25 |
| Last Modified: | 15 Sep 2021 05:25 |
| URI: | http://eprints.lums.ac.ir/id/eprint/2992 |
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