Potential Roles of MyomiRs in Cardiac Development and Related Diseases

M. Sarabi, Mostafa and Abkhooie, Leila and Kahroba, Houman and Eyvazi, Shirin and Tarhriz, Vahideh (2021) Potential Roles of MyomiRs in Cardiac Development and Related Diseases. Current cardiology reviews.

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Abstract

Muscle-specific miRNAs, which are known as MyomiRs, are crucial regulatory elements for cardiovascular development. MyomiRs are abundantly expressed in the myocardium and regulate certain aspects of physiological and pathological processes in myocardiocytes, including cardiovascular development, myocardial remodeling, and arise for cardiovascular diseases through different mechanisms, such as epigenetic pathways. Clinical and experimental studies have confirmed the myomiRs as promising diagnostic biomarkers for the early diagnosis of cardiac disorders. In this review, we have summarized recent findings in the field of epigenetic modulations of myomiRs and cardiac regeneration associated with cardiac diseases. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Item Type: Article
Subjects: R Medicine > RC Internal medicine
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samira sepahvandy
Date Deposited: 14 Sep 2021 07:52
Last Modified: 14 Sep 2021 07:52
URI: http://eprints.lums.ac.ir/id/eprint/2986

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