The Experimental Role of Medicinal Plants in Treatment of Toxoplasma gondii Infection: A Systematic Review

Cheraghipour, Kourosh and Masoori, Leila and Ezzatpour, Behrooz and Sheikhian, Ali and Malekara, Vahid and Niazi, Massumeh and Moradpour, Kobra and Mahmoudvand, Hossein (2020) The Experimental Role of Medicinal Plants in Treatment of Toxoplasma gondii Infection: A Systematic Review. Acta Parasitol.

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Background: Toxoplasma gondii is the global protozoa that could cause contamination in warm-blooded animals and is considered among the opportunistic pathogens in immunocompromised patients. Among the people at risk, toxoplasmosis infection can lead to the incidence of severe clinical manifestations, encephalitis, chorioretinitis, and even death. Purpose: The present research is focused on the new research for the treatment of toxoplasmosis parasitic disease using medicinal herbs. Methods: The search was performed in five English databases, including Scopus, PubMed, Web of Science, EMBASE, and Google Scholar up from 2010 to December 2019. Studies in any language were entered in the searching step if they had an English abstract. The words and terms were used as a syntax with specific tags of each database. Results: Out of 1832 studies, 36 were eligible to be reviewed. The findings showed that 17 studies (47%) were performed in vitro, 14 studies (39%) in vivo, and 5 studies (14%) both in vivo and in vitro. Conclusion: The studies showed that the plant extracts can be a good alternative in reducing the toxoplasmosis effects in the host and the herbal extracts can be used to produce natural product-based drugs affecting toxoplasmosis with fewer side-effects than synthetic drugs. Keywords: Herbal medicine; Medicinal plants; Systematic review; Toxoplasma gondii; Treatment.

Item Type: Article
Subjects: R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samira sepahvandy
Date Deposited: 14 Aug 2021 04:33
Last Modified: 14 Aug 2021 04:33

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