The emerging role of probiotics as a mitigation strategy against coronavirus disease 2019 (COVID‑19)

Mirzaei, Rasoul and Talei, Gholam-Reza and Attar, Adeleh and Papizadeh, Saher and Salimi Jeda, Ali and Jamasbi, Elaheh (2021) The emerging role of probiotics as a mitigation strategy against coronavirus disease 2019 (COVID‑19). Archives of Virology.

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COVID-19 is an acute respiratory infection accompanied by pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has afected millions of people globally. To date, there are no highly efcient therapies for this infection. Probiotic bacteria can interact with the gut microbiome to strengthen the immune system, enhance immune responses, and induce appropriate immune signaling pathways. Several probiotics have been confrmed to reduce the duration of bacterial or viral infections. Immune ftness may be one of the approaches by which protection against viral infections can be reinforced. In general, prevention is more efcient than therapy in fghting viral infections. Thus, probiotics have emerged as suitable candidates for controlling these infections. During the COVID-19 pandemic, any approach with the capacity to induce mucosal and systemic reactions could potentially be useful. Here, we summarize fndings regarding the efectiveness of various probiotics for preventing virus-induced respiratory infectious diseases, especially those that could be employed for COVID-19 patients. However, the benefts of probiotics are strain-specifc, and it is necessary to identify the bacterial strains that are scientifcally established to be benefcial.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samira sepahvandy
Date Deposited: 12 Apr 2021 04:43
Last Modified: 12 Apr 2021 04:43

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