Congenital Heart Disease in non-Diabetic Large-for-Gestational-Age (LGA) Neonates

Firouzi, Majid and Sherkatolabbasieh, Hamidreza and Nezami, Ali Reza and Shafizadeh, Shiva (2020) Congenital Heart Disease in non-Diabetic Large-for-Gestational-Age (LGA) Neonates. Cardiovasc Hematol Disord Drug Targets ..

Full text not available from this repository.


Abstract Background: Congenital heart diseases are the most prevalent congenital abnormalities in the neonates, caused by the environmental and genetic factors and contribute to the leading cause of death. The aim of this study is to evaluate the relationship between neonates with large for gestational age and increased risk of congenital heart diseases among nondiabetic mothers. Methods: In this study, 179 neonates with large for gestational age in Khorramabad were enrolled where heart abnormalities were evaluated using echocardiography. Results: 87 neonates had more than 4000 g of the birth weight with no heart abnormalities and 92 (51%) macrosomic neonates had congenital heart diseases. Statistical analysis revealed that there was a significant relationship between birth weight and increased risk of acquiring congenital heart disease between the two groups. There was no significant relationship between birth weight, maternal age, gender, labor type and blood group between the two groups. The highest incidence of congenital heart anomalies was related to 38% of arterial septal defect (ASD) and 15.2% of ASD and VSD, respectively. Conclusion: The most prevalent abnormality was arterial septal ASD. None of these abnormalities were associated with maternal age, birth weight and neonate gender. Future studies for congenital heart disease and neonatal birth weight are therefore, recommended. Keywords: Congenital heart abnormalities; birth weight; heart abnormalities.; large for gestational age; maternal age; neonatal

Item Type: Article
Subjects: R Medicine > RJ Pediatrics
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samira sepahvandy
Date Deposited: 20 Dec 2020 04:44
Last Modified: 20 Dec 2020 04:44

Actions (login required)

View Item View Item