Dose-response meta-analysis of arsenic exposure in drinking water and intelligence quotient

Hasanvand, Mahsa and Mohammadi, Mohsen and Khoshnamvand, Nahid and Jafari, Ali and Safari Palangi, Hossein and Mokhayeri, Yaser (2020) Dose-response meta-analysis of arsenic exposure in drinking water and intelligence quotient. J Environ Health Sci Eng.

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Objectives: Exposure to inorganic arsenic through drinking water is a threat for public health. Using the arsenic-containing water in the long-term causes a variety of skin diseases, high blood pressure, and skin cancer. Arsenic also damages the nervous system. A wide range of studies have studied the effect of arsenic in drinking water on the level of intelligence in children. Methods: For the purpose of our research, we searched three electronic databases including Scopus, Web of Science, and Medline (PubMed) in English from 2000 to January 2018. We used the dose-response meta-analysis through applying random effect models in order to estimate the pooled association (with a 95% uncertainty) between water arsenic concentration and intelligence level. Results: Using a two-stage random effect model to investigate the dose-response association between arsenic concentration and Intelligence Quotient scale, we estimated a significant linear association as -0.08 (95% CI: -0.14, -0.01). Actually, for each unit increase in arsenic concentration (one microgram per liter), intelligence quotient scale decreases by 0.08%. Conclusions: Considering the significance of the relationship between arsenic concentration in drinking water and the level of intelligence quotient as an important factor in training, the level of arsenic and its associated risks should be decreased in water resources. Keywords: Arsenic; Dose-response; Drinking water; Intelligence quotient.

Item Type: Article
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samira sepahvandy
Date Deposited: 19 Dec 2020 07:00
Last Modified: 19 Dec 2020 07:00

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