Effects of gradual weight loss v. rapid weight ‎loss on body composition and RMR: a ‎systematic review and meta-analysis

Abbasnezhad, Amir and Bagheri, Reza and Ashtary-Larky, Damoon and Alipour, Meysam and Wong, Alexei (2020) Effects of gradual weight loss v. rapid weight ‎loss on body composition and RMR: a ‎systematic review and meta-analysis. Br J Nutr.

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This systematic review and meta-analysis compared the effects of different rates of weight ‎loss (WL), but equivalent total WL, on body composition and RMR. Studies examining ‎gradual v. rapid WL on body composition and RMR in participants with ‎overweight/obesity published up to October 2019 were identified through PubMed, the ‎Cochrane Library, Web of Science, Embase, Scopus and Ovid databases. Meta-analysis ‎was carried out using a fixed or random effects model as appropriate. Although the ‎magnitude of WL was similar (mean difference 0·03 kg, 95 % CI –0·65, 0·71), gradual WL ‎promoted greater reductions in fat mass (FM) (–1 kg, 95 % CI –1·70, –0·29) and body fat ‎percentage (BFP) (–0·83 %, 95 % CI –1·49, –0·17). Gradual WL significantly preserved ‎RMR compared with rapid WL (407·48 kJ, 95 % CI 76·76, 118·01). However, there was no ‎significant difference in waist and hip circumferences, waist:hip ratio and fat-free mass ‎‎(FFM) between gradual and rapid WL. The present systematic review and meta-analysis ‎indicates beneficial effects of gradual WL, as compared with rapid WL, on FM, BFP and ‎RMR in individuals with overweight/obesity. However, FFM changes and anthropometric ‎indices did not significantly differ following different rates of WL.‎

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samira sepahvandy
Date Deposited: 16 Dec 2020 15:16
Last Modified: 16 Dec 2020 15:16
URI: http://eprints.lums.ac.ir/id/eprint/2499

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