Effect of ambient air pollution and ‎temperature on the risk of stillbirth: a ‎distributed lag nonlinear time series ‎analysis

Ranjbaran, Mehdi and Mohammadi, Rasool and Yaseri, Mehdi and Kamari, Mehdi and Habibelahi, Abbas (2020) Effect of ambient air pollution and ‎temperature on the risk of stillbirth: a ‎distributed lag nonlinear time series ‎analysis. JOURNAL OF ENVIRONMENTAL HEALTH SCIENCE AND ENGINEERING. ISSN 2052-336X

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Objectives This study aimed to determine the effect of ambient air pollution and temperature on ‎stillbirth in Tehran.‎ Methods In this time-series study, the effect of O3 (ppb), CO (ppm), NO2 (ppb), SO2 (ppb), ‎PM2.5 (μg/m3), and minimum, maximum, and mean daily temperature (°C) on stillbirth was ‎evaluated in Tehran, Iran between March 2015 and March 2018. Using a quasi-Poisson ‎regression model in combination with a Distributed Lag Non-linear Models (DLNM), the ‎Relative Risk (RR) was estimated through comparing the high temperature (99th, 95th, ‎and 75th percentiles) and low temperature (1st, 5th, and 25th percentiles) with the median. ‎The effect of air pollution was estimated for each 1-, 5-, or 10-unit increase in the ‎concentration during lags (days) 0–21.‎ Results Among air pollutants, only a 5-ppm increase in the SO2 concentration in lag 0 increased the ‎risk of stillbirth significantly (RR = 1.062; 1.002–1.125). The largest effect of heat was ‎observed while comparing the 99th percentile of minimum daily temperature (26.9 °C) with ‎the median temperature (13.2 °C), which was not statistically significant (RR = 1.25; 0.95–‎‎1.65). As for cold, a non-significant protective effect was observed while comparing the 1st ‎percentile of maximum daily temperature (3.1 °C) with the median temperature (23.2 °C) ‎‎(RR = 0.92; 0.72–1.19).‎ Conclusion Each 5-ppm increase in the mean daily SO2 in lag 0 increased the risk of stillbirth by 6% ‎while other air pollutants had no significant effects on stillbirth. In lags 0 and 1, the heat ‎increased the risk of stillbirth while the cold had protective effects, which were not ‎statistically significant.‎

Item Type: Article
Subjects: R Medicine > RJ Pediatrics > RJ101 Child Health. Child health services
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samira sepahvandy
Date Deposited: 16 Dec 2020 06:38
Last Modified: 16 Dec 2020 06:38
URI: http://eprints.lums.ac.ir/id/eprint/2469

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