Dose-response meta-analysis of arsenic exposure in drinking water and ‎intelligence quotient

Hasanvand, Mahsa and Mohammadi, Rasool and Khoshnamvand, Nahid and Jafari, Ali and Mokhayeri, Yaser (2020) Dose-response meta-analysis of arsenic exposure in drinking water and ‎intelligence quotient. Journal of Environmental Health Science and Engineering ‎.

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Objectives Exposure to inorganic arsenic through drinking water is a threat for public health. Using the arsenic-‎containing water in the long-term causes a variety of skin diseases, high blood pressure, and skin cancer. ‎Arsenic also damages the nervous system. A wide range of studies have studied the effect of arsenic in ‎drinking water on the level of intelligence in children.‎ Methods For the purpose of our research, we searched three electronic databases including Scopus, Web of ‎Science, and Medline (PubMed) in English from 2000 to January 2018. We used the dose-response meta-‎analysis through applying random effect models in order to estimate the pooled association (with a 95% ‎uncertainty) between water arsenic concentration and intelligence level.‎ Results Using a two-stage random effect model to investigate the dose-response association between arsenic ‎concentration and Intelligence Quotient scale, we estimated a significant linear association as −0.08 (95% ‎CI: −0.14, −0.01). Actually, for each unit increase in arsenic concentration (one microgram per liter), ‎intelligence quotient scale decreases by 0.08%.‎ Conclusions Considering the significance of the relationship between arsenic concentration in drinking water and the ‎level of intelligence quotient as an important factor in training, the level of arsenic and its associated ‎risks should be decreased in water resources.‎

Item Type: Article
Subjects: R Medicine > RM Therapeutics. Pharmacology
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samira sepahvandy
Date Deposited: 16 Dec 2020 05:55
Last Modified: 16 Dec 2020 05:55

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