Protective effects of royal jelly on testicular torsion induced ischaemia reperfusion injury in rats

Gholami, Mohammadreza and Anbari, Khatereh and Tavakoli, Negin and Abbaszadeh, Abolfazl (2020) Protective effects of royal jelly on testicular torsion induced ischaemia reperfusion injury in rats. Journal Andrologia.

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Abstract

This study was performed to investigate the protective effects of royal jelly (RJ) on a testicular torsion‐induced ischaemia/reperfusion (I/R) injury in adult rats. A total of 40 male Wistar rats were divided into four groups, including 10 rats in each group: Group 1 (sham), Group 2 (Control), group 3 (I/R rats treated with 100 mg/kg RJ for 50 days after torsion) and group 4( I/R rats treated with 20 mg/kg vitamin C for 50 days after torsion). Testicular torsion was created by rotating the right testes 720° a clockwise direction for 90 min. The levels of testosterone were measured by ELISA. Pathological evaluation, mean maturity and quality of the seminiferous tubules were used. Results showed that the testicular histopathology standards and testosterone levels changes were statistically significant in groups 3 and 4. The results obtained in this study may suggest that RJ like vitamin C had protective effects on a testicular ischaemia/reperfusion‐induced injury in rats.

Item Type: Article
Subjects: R Medicine > RB Pathology
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: lorestan university
Date Deposited: 30 Jun 2020 03:49
Last Modified: 30 Jun 2020 03:49
URI: http://eprints.lums.ac.ir/id/eprint/2204

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