The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension

Ghafarzadeh, Masoumeh and Shakarami, Amir and Yari, Fatemeh and Namdari, Parsa (2020) The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension. Hypertension in Pregnancy.

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Abstract

Objective: The aim of the study was to compare the complication of Antihypertensive drug; in pregnant women with chronic hypertension. Method: This retrospective cohort study was performed on 300 pregnant women with chronic hypertension. Results: a relative risk of preeclampsia among methyldopa group was 3.45 times higher than the metoprolol, the relative risk of preterm labor was not significantly between methyldopa and metoprolol group, LBW, and IUGR in methyldopa and amlodipine groups . Conclusion: Methyldopa and amlodipine are associated with the least side effects in pregnant women treated for chronic hypertension.the incidence of preeclampsia was greater in methyldopa group.

Item Type: Article
Subjects: R Medicine > RG Gynecology and obstetrics
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samad darabian
Date Deposited: 30 May 2020 08:41
Last Modified: 30 May 2020 08:41
URI: http://eprints.lums.ac.ir/id/eprint/2127

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