Lorzadeh, Nahid and Kazemirad, Nastaran (2020) The Role of Natural Killer Cells and Mast Cells in Female Infertility and Associated Treatment Outcomes. Current Women`s Health Reviews.
Full text not available from this repository.Abstract
ntroduction One of the identified causes of infertility has been related to the inability to regulate immunological tolerance of the maternal immune system against the developing fetus thereby inhibiting the process of implantation. Various immune cells that have identified to contribute to the concept of un-regulated immunological tolerance such as mast cells (MCs) and natural killer cells (NK). There are available evidences that MC play a role in the pathogenesis of infertility diseases like endometriosis and NK in specific infertility disease. Objective Presently, there are studies to formulate and develop immunosuppressive drugs in order to suppress or inhibit the process of immune rejection caused by maternal immune cells. In addition, there have been reports regarding the use of steroids for the treatment of miscarriage that can inhibit the activity of most immune cells. Conclusion This review is to give a comprehensive mini-review on the role of immune cells, especially mast cells and NK cells in developing novel infertility treatment.
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > RB Pathology |
| Divisions: | Faculty of Medicine, Health and Life Sciences > School of Medicine |
| Depositing User: | lorestan university |
| Date Deposited: | 18 May 2020 04:38 |
| Last Modified: | 18 May 2020 04:38 |
| URI: | http://eprints.lums.ac.ir/id/eprint/2106 |
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