Effect of daily probiotic yogurt consumption on inflammation: A systematic review and meta-analysis of randomized Controlled Clinical trials

Mousavi, Seyedeh Neda and Saboori, Somayeh and Asbaghi, Omid (2020) Effect of daily probiotic yogurt consumption on inflammation: A systematic review and meta-analysis of randomized Controlled Clinical trials. Obesity Medicine.

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Abstract

A systematically search was done to find clinical trials published in databases including PubMed, Cochrane's library, ISI web of Science, Scopus, and Ovid from the beginning up to November 2019 to assess the effects of daily probiotic yogurt consumption on serum levels of C-reactive protein (CPR), tumor-necrosis factor-α (TNF-α), and interleukin (IL)-6. From 2193 papers, excluding duplicates, nine studies were included in this meta-analysis. Results The pooled random-effect size analysis of nine trials showed significant effect of daily probiotic yogurt consumption on serum CRP levels [WMD (−0.26), (95% CI -0.42 to −0.09), p = 0.002], but no considerable effect was seen on TNF-α [WMD (−0.32), (95% CI -2.25 to 1.6), p = 0.74] and IL-6 [WMD (−0.2), (95%CI -0.53 to 0.14), p = 0.25]. The subgroup analysis showed that daily probiotic yogurt consumption significantly reduced serum CRP levels in the doses lower than 200 g, for more than eight weeks in the overweight participants (25 < BMI<29.9 kg/m2) with the baseline CRP levels <3 (mg/dl). Conclusions Daily probiotic yogurt consumption for more than eight weeks showed beneficial effect on serum CRP levels in overweight people.

Item Type: Article
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: lorestan university
Date Deposited: 12 May 2020 07:18
Last Modified: 12 May 2020 07:18
URI: http://eprints.lums.ac.ir/id/eprint/2067

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