Effects of Adjuvant Ketamine on Induction of Anesthesia for the Cesarean Section.

Moradkhani, Mahmoud Reza and Beiranvand, Siavash and Nadri, Sedigheh and Hejri, P (2020) Effects of Adjuvant Ketamine on Induction of Anesthesia for the Cesarean Section. Curr Clin Pharmacol.

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BACKGROUND: The cesarean section has shown an increase in the trends within the past few years. The use of appropriate and effective anesthesia for the procedure is important, not only to reduce the incidence of maternal and fetal morbidities but also to reduce the incidence of intraoperative awareness. OBJECTIVE: The aim of this study is to evaluate the intraoperative and postoperative effects of adjuvant ketamine, when used in combination with general anesthesia. METHODS: The study was conducted on the patients referred to Asali hospital for the cesarean section. 100 patients were assigned to two groups. Patients in Group A received thiopental (4 mg / kg) as an anesthetic agent for the surgery whereas; those in group B received thiopental along with 0.5 mg / kg of intravenous ketamine. The effects of ketamine such as, depth of anesthesia, intraoperative and postoperative awareness, vomiting and hallucination were recorded in the questionnaire and data were statistically analyzed using SPSS v25. RESULTS: Of 100 patients in group A, 10 of them were not deeply unconscious. 40 patients in group A and 25 in group B had intraoperative awareness. 1 patient in group A and 3 in group B had vomiting and 1 patient in group B was presented with the hallucinations. CONCLUSION: Overall use of ketamine is associated with better sedation and no significant side effects with low doses of ketamine, were seen in our study. Comparative studies using other analgesics, with larger sample size are therefore recommended. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net. KEYWORDS: Anesthesia; Cesarean Section; Deep unconsciousness; Hallucination; Ketamine; Sedation

Item Type: Article
Subjects: R Medicine > RG Gynecology and obstetrics
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samira sepahvandy
Date Deposited: 10 May 2020 07:00
Last Modified: 10 May 2020 07:00
URI: http://eprints.lums.ac.ir/id/eprint/2038

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