Mahmoudvand, Hossein and Mirzaei, Mojgan and Khatami, Mehrdad and Mahmoudvand, Hormoz and Kheirandish, Farnaz and Niazi, Massumeh and Sepahvand, Farnaz and Nadri*, Sedigheh (2019) In vitro and ex vivo effects of Quercus infectoria extract on hydatid cyst protoscolecs. Yafteh, 21 (3).
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Abstract
Background: This study aims to evaluate the scolicidal effects of oak (Quercus infectoria) extract on hydatid cyst protoscoleces in vitro and ex vivo. Materials and Methods: Following the collection of protoscoleces from sheep livers infected with fertile hydatid cysts from a slaughterhouse in Khorramabad, they were treated with various concentrations of oak extract (250-1000 µg/mL) for 5-40 min in vitro and ex vivo. Finally the mortality of protoscoleces was assessed by the eosin exclusion test (0.1% eosin staining). Results: The mean of the mortality of protoscoleces was 100% after 5 min incubation with the concentration of 1000 mg/ml of oak extract. On the other hand, the mean of the mortality of protoscoleces after 10 incubation with the concentration of 500 mg/ml of oak extract was 100%. However, these results were not observed in the ex vivo analysis. That is, oak extract requires a longer length of time to display potent protoscolicidal effects. Conclusion: The results of this investigation revealed that oak extract could have a significant scolicidal activity on hydatid cyst protoscoleces. However, further research, particularly in human and animal subjects, is required to reach this conclusion. Keywords: Hydatidosis, Echinococcus granulosus, extract, hydatid sand, hcolicidal
| Item Type: | Article |
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| Subjects: | R Medicine > RD Surgery R Medicine > RZ Other systems of medicine |
| Depositing User: | mania jalilvand |
| Date Deposited: | 10 Dec 2019 04:33 |
| Last Modified: | 10 Dec 2019 04:33 |
| URI: | http://eprints.lums.ac.ir/id/eprint/1874 |
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