Brodifacoum toxicosis and abortion in an Arabian mare

Zakian, A and Mami, S and Nouri, M and Jalali, SM and Tehrani-Sharif, M (2019) Brodifacoum toxicosis and abortion in an Arabian mare. Vet Res Forum., 10 (2). pp. 173-176.

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A 3-year-old pregnant Arabian mare was referred to the Veterinary Teaching Hospital of Shahid Chamran University of Ahvaz with a history of bleeding and rodenticide ingestion. The results of paraclinical examinations showed severe normocytic and normochromic anemia, decreased serum total protein, albumin, and fibrinogen concentrations, increased serum total bilirubin, urea, and creatinine concentrations, as well as increased serum aspartate aminotransferase and creatine kinase activity. Three days after treatment, all the clinical signs were resolved, however, fetus abortion occurred. In order to confirm the suspected cause of abortion and toxicosis, high-performance liquid chromatography was performed on serum sample of mare and liver tissue of the aborted fetus and toxicosis was confirmed. Poisoning with brodifacoum is considered as an important and lethal poisoning for both human being and animals. To our knowledge, this is the first report of spontaneous toxicosis and abortion with brodifacoum. Brodifacoum toxicosis can be effectively managed with early diagnosis, good paraclinical examinations and appropriate treatment.

Item Type: Article
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samira sepahvandy
Date Deposited: 19 Aug 2019 07:07
Last Modified: 19 Aug 2019 07:07

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