SEROMOLECULAR ASSESS OF TOXOPLASMA GONDIIINFECTION IN PREGNANT WOMEN AND NEONATAL UMBILICAL CORD BLOOD

Rashno, Mohammad Menati and Fallahi, Shirzad and Arab-Mazar, Zahra and Dana, Hassan (2019) SEROMOLECULAR ASSESS OF TOXOPLASMA GONDIIINFECTION IN PREGNANT WOMEN AND NEONATAL UMBILICAL CORD BLOOD. EXCLI JOURNAL, 18.

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Abstract

Toxoplasmosis is considered as one of the most prevalent human parasitic infections that can be transmitted from mother to the fetus. The onset of toxoplasmosis during pregnancy has clinical complications including spontaneous abortion, preterm labor, stillbirth and fetal abnormalities. The aim of this study was to investigate the prevalence of Toxoplasmosis infection in pregnant women and their infants in Lorestan province, Western Iran. Blood and sera samples were collected from 98 pregnant women and their infants. All collected samples were examined for Toxoplasma gondii infection by serological tests (ELISA IgM & IgG) and PCR assay. Among the 98 samples of mother and umbilical cord prevalence of anti-Toxoplasma IgG, was 34/98 (34.69 %) and 33/98 (33.67 %), respectively. All pregnant women were negative for, anti-Toxoplasma IgM while it was found in 5/98 (5.1 %) of umbilical cords. Based on PCR analysis, Toxoplasma infection was detected in 5 (5.1 %) and 7 (7.14 %) of mother and umbilical cords, respectively. Molecular test along with evaluation of IgM (P <0.001) and IgG (P = 0.001) were significantly correlated.

Item Type: Article
Subjects: R Medicine > RZ Other systems of medicine
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: sobhan rezaiian
Date Deposited: 20 Jan 2019 04:59
Last Modified: 20 Jan 2019 04:59
URI: http://eprints.lums.ac.ir/id/eprint/1526

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