Evaluation of antimicrobial activity of synthesised silver nanoparticles using Thymus kotschyanus aqueous extract

Gholami, Maryam and Shahzamani, Kiana and Marzban, Abdolrazagh and Lashgarian, Hamed Esmaeil (2018) Evaluation of antimicrobial activity of synthesised silver nanoparticles using Thymus kotschyanus aqueous extract. IET NANOBIOTECHNOLOGY, 12 (8). pp. 1114-1117.

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Abstract

Development of a green chemistry process for the synthesis of silver nanoparticles (AgNPs) has become a focus of interest. Characteristics of AgNPs were determined using techniques, such as ultraviolet-visible spectroscopy (UV-vis), Fourier transform infrared (FTIR) analysis, scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy and X-ray diffraction (XRD). The synthesised AgNPs using Thymus kotschyanus had the most growth inhibition against gram-positive bacteria such as Staphylococcus aureus and Bacillus subtilise, while the growth inhibition of AgNPs at 1000-500 mu g/ml occurred against Klebsiella pneumonia and at 1000-250 mu g/ml of AgNPs was observed against E. coli. The UV-vis absorption spectra confirmed the formation of the AgNPs with the characteristic peak at 415nm and SEM micrograph acknowledged spherical particles in a nanosize range. FTIR measured the possible biomolecules that are responsible for stabilisation of AgNPs. XRD analysis exhibited the crystalline nature of AgNPs and showed face-centred cubic structure. The synthesised AgNPs revealed significant antibacterial activity against gram-positive bacteria.

Item Type: Article
Subjects: Q Science > QD Chemistry
R Medicine > RZ Other systems of medicine
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: sobhan rezaiian
Date Deposited: 22 Dec 2018 11:27
Last Modified: 22 Dec 2018 11:27
URI: http://eprints.lums.ac.ir/id/eprint/1515

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