Carcinogenic and non-carcinogenic health risks of metal(oid)s in tap water from Ilam city, Iran

Fakhri, Yadolah and Saha, Narottam and Ghanbari,, Sahebeh and Rasouli, Milad and Miri, Ali and Avazpour, Moayed and Rahimizadeh, Aziz and Riahi, Seyed-Mohammad) and Ghaderpoori, Mansour and Keramati, Hassan and Moradi, Bigard and Amanidaz, Nazak and Khaneghah, Amin Mousavi (2018) Carcinogenic and non-carcinogenic health risks of metal(oid)s in tap water from Ilam city, Iran. FOOD AND CHEMICAL TOXICOLOGY, 118. pp. 204-211.

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One of the most important pathways for exposure to metals is drinking water ingestion. Chronic or acute exposure to metals can endanger the health of the exposed population, and hence, estimation of human health risks is crucial. In the current study for the first time, the concentrations of Mercury (Hg), Arsenic (As), Zinc (Zn), Lead (Pb) and Cobalt (Co) in 120 collected tap water samples (2015, July-November) from Ilam city, Iran were investigated using flame atomic absorption spectrophotometer. Also, the metal-induced carcinogenic and noncarcinogenic risks for consumers exposed to tap drinking water were calculated. The average (range) concentrations of Hg, Zn, As, Pb and Co were defined as 0.40 +/- 0.10 mu g/L (ND-0.9 pg/L), 5014 +/- 5707 mu g/L (2900.00-5668.33 mu g/L), 21.008 +/- 2.876 mu g/L (3.5-62 mu g/L), 30.38 +/- 5.56 mu g/L (6-87 mu g/L), and 11.34 +/- 1.61 mu g/L (0.1-50 mu g/L), respectively. Average concentrations of all examined metals were significantly higher than WHO and national standard recommended limits. The ranking order of metals concentrations in the tap drinking water was Zn > Pb > As > Co > Hg. Except for Hg and Co, at least one age group consumers were at considerable non-carcinogenic risks induced by Zn, As and Pb [Target Hazard Quotient (THQ > 1)]. The rank order of age groups consumers based on THQ and Incremental lifetime cancer risk (ILCR) was < 1 years > 1-9 years > 20 + years > 10-19 years. The calculated ILCR for As in all age groups were higher than 10(-3) value. All age groups of consumers in Ilam city, especially infants (< 1 years) and children (1-10 years), are at considerable non-carcinogenic and carcinogenesis risk.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samira sepahvandy
Date Deposited: 24 Sep 2018 06:26
Last Modified: 24 Sep 2018 06:26

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