Diabetic ulcer regeneration: stem cells, biomaterials, growth factors.

Zarei, F and Negahdari, B and Eatemadi, A (2018) Diabetic ulcer regeneration: stem cells, biomaterials, growth factors. Artif Cells Nanomed Biotechnol, 46. pp. 26-32.

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Official URL: http://www.tandfonline.com/doi/abs/10.1080/2169140...


Abstract The impairment of ulcer wound healing in diabetic patients is a vital clinical problem affecting millions of patients. Several clinical and basic science studies have demonstrated that stem cell therapy, to be effective in healing diabetic ulcer. Furthermore, these ulcer wounds may be healed from molecular maneuvering of growth factors to improve microcirculation within the ulcer wound. In addition, ulcer wound dressings may be employed as medicated systems, through the delivery of drugs, growth factors, peptides and stem cells. These dressing materials can include natural, modified and synthetic polymers, as well as their mixtures or combinations. This review paper will give a summary of some of the recent advances on the application of stem cells, biomaterials and growth factors in the treatment of diabetic ulcer wound. KEYWORDS: Diabetic ulcer; biomaterials; growth factors; stem cells; wound dressings

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: samira sepahvandy
Date Deposited: 28 Jan 2018 20:49
Last Modified: 28 Jan 2018 20:49
URI: http://eprints.lums.ac.ir/id/eprint/1157

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