Diabetic ulcer regeneration: stem cells, biomaterials, growth factors

Zarei, Farshad and Negahdari, Babak and Eatemadi, Ali (2017) Diabetic ulcer regeneration: stem cells, biomaterials, growth factors. Journal Artificial Cells, Nanomedicine, and Biotechnolog An International Journal. pp. 1-7.

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/28355923

Abstract

The impairment of ulcer wound healing in diabetic patients is a vital clinical problem affecting millions of patients. Several clinical and basic science studies have demonstrated that stem cell therapy, to be effective in healing diabetic ulcer. Furthermore, these ulcer wounds may be healed from molecular maneuvering of growth factors to improve microcirculation within the ulcer wound. In addition, ulcer wound dressings may be employed as medicated systems, through the delivery of drugs, growth factors, peptides and stem cells. These dressing materials can include natural, modified and synthetic polymers, as well as their mixtures or combinations. This review paper will give a summary of some of the recent advances on the application of stem cells, biomaterials and growth factors in the treatment of diabetic ulcer wound.

Item Type: Article
Subjects: R Medicine > RZ Other systems of medicine
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: sobhan rezaiian
Date Deposited: 28 Dec 2017 09:54
Last Modified: 28 Dec 2017 09:54
URI: http://eprints.lums.ac.ir/id/eprint/1125

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