Rapid Weight Loss vs. Slow Weight Loss: Which is More Effective on Body Composition and Metabolic Risk Factors?

Ashtary-Larky, Damoon and Ghanavati, Matin and Lamuchi-Deli, Nasrin and Payami, Seyedeh Arefeh and Alavi-Rad, Sara and Boustaninejad, Mehdi and Afrisham, Reza and Abbasnezhad, Amir and Alipour, Meysam (2017) Rapid Weight Loss vs. Slow Weight Loss: Which is More Effective on Body Composition and Metabolic Risk Factors? INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM, 15. ISSN 1726-913X

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Abstract

Background: Achieving weight loss (WL) in a short time regardless of its consequences has always been the focus of many obese and overweight people. In this study, anthropometric and metabolic effects of two diets for rapid and slow WL and their consequences were examined. Methods: Forty-two obese and overweight individuals were randomly divided to 2 groups; rapid WL (weight loss of at least 5% in 5 weeks) and slow WL (weight loss of at least 5% in 15 weeks). To compare the effects of the rate of WL in 2 groups, the same amount of was achieved with different durations. Anthropometric indices, lipid, and glycemic profiles, and systolic and diastolic blood pressures were evaluated before and after the intervention. Results: Both protocols of rapid WL and slow WL caused reduction in waist circumference, hip circumference, total body water, body fat mass, lean body mass, and resting metabolic rate (RMR). Further reduction in waist circumference, hip circumference, fat mass, and percentage of body fat was observed in slow WL and decreased total body water, lean body mass, fat free mass, and RMR was observed in rapid WL. Improvement in lipid and glycemic profiles was observed in both groups. Reduction of low-density lipoprotein and fasting blood sugar, improvement of insulin resistance, and sensitivity were more significant in rapid WL in comparison to slow WL. Conclusions: Weight Loss regardless of its severity could improve anthropometric indicators, although body composition is more favorable following a slow WL. Both diets improved lipid and glycemic profiles. In this context, rapid WL was more effective. (IRCT2016010424699N2) Keywords Author Keywords:Body Composition; Diet; Insulin Resistance; Obesity; Weight Loss KeyWords Plus:TYPE-2 DIABETIC-PATIENTS; GLYCEMIC CONTROL; OBESE-PATIENTS; LIPID PROFILE; FAT DIET; OVERWEIGHT; TRIAL; INFLAMMATION; INDIVIDUALS; MAINTENANCE

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: sobhan rezaiian
Date Deposited: 10 Dec 2017 14:28
Last Modified: 10 Dec 2017 14:28
URI: http://eprints.lums.ac.ir/id/eprint/1046

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